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This is the second in a series of articles related to nutrition during the treatment of paediatric cancer. The first article was an introduction and covered the general causes of malnutrition during treatment.
The focus on pre-conception nutrition and foetal health is important for women and men because optimal nutrition during pregnancy actually begins pre-conceptually, and developing foetuses depend solely on the transfer of nutrients from the bodies of the mothers carrying them1.
nutrition in the womb encompasses not only maternal health history and nutrition, but also paternal nutrition and the health of sperm before conception
Gene expression can be promoted or altered by nutrients during pregnancy, childhood, and throughout the life-cycle. The importance of nutrition throughout the life-cycle which begins before conception cannot be refuted2. Health professionals have recognized the effects of proper nutrition before conception on the health of the infant and its mother. However, “nutrition in the womb” encompasses not only maternal health history and nutrition, but also paternal nutrition and the health of sperm before conception.
Cancer involves the abnormal division and reproduction of cells that can spread throughout the body. It’s a disease characterized by abnormal cell growth and can occur in any organ. The genes lose control of cell-growth and cell-reproduction becomes unstructured and excessive, thus leading to development of a tumor. The precise etiology of cancer is not known, but heredity, viruses, environmental carcinogens, and possibly emotional stress contribute to its development3.
Although only approximately 5% to 10% of all cancers occur as a result of inherited genetic alterations, both parents are advised to avoid any form of exposure to carcinogenic compounds in their environment which could damage DNA or alter cell-division, in order to maintain optimum reproductive health and also give birth to a healthy child4.
Exposure of men and women to environmental chemicals, including pesticides, heavy metals, and organic solvents, is associated with an increased risk of producing a child with congenital anomalies5.
Some of the potential risk factors for the development of congenital anomalies in foetuses include;
Studies have shown a positive correlation between the mother’s diet and the health of the baby at birth. It is also thought that the woman who consumed a nutritious diet before pregnancy is more apt to bear a healthy infant than one who did not. Exposure to environmental carcinogens increases the risk of alteration in the genetic make-up of the parents or the child, which invariably increases the risk of cancer development13. Knowing the carcinogens we are exposed to in our environment and avoiding them is paramount in the fight to reduce the cases of paediatric cancer.
Our next article in this series will cover nutrition during pregnancy.Photos by Eduardo Cabrera, Sebastián León Prado and Annie Spratt via Unsplash.
Notes [ + ]
|1.||↲||Simon, J. Promoting Fertility Via Optimal Nutrition: Nutrition in Infertility Prevention and Management. 2014.|
|2.||↲||Poludowski, P., Holick, M. F., & Pilz, S. (2013). “Vitamin D Effects on Musculoskeletal Health, Immunity, Autoimmunity, Cardiovascular Disease, Cancer, Fertility, Pregnancy, Dementia and Mortality—A Review of Recent Evidence.” Autoimmun Rev, 12, 976.|
|3.||↲||Roth, R. A. Nutrition and Diet Therapy. New York: Cengage, 2017.|
|4.||↲||Ramakrishan, U., Grant, F., & Goldenberg, T. (2012). “Effects Before and During Early Pregnancy on Maternal and Infant Outcomes: A Systematic Review.” Paediatr Perinat Epidomiol, 285.|
|5, 7.||↲||Van, Z. d., De Wart, G., & Steegers, E. A. (2013). “Ethical Aspects of Paternal Preconception Lifestyle Medication.” Am J Obstet Gynecol, 209, 11.|
|6.||↲||Jensen, T. K., Gottschau, M., & Madsen, J. O. (2014). “Habitual Alcohol Consumption Associated with Reduced Semen Quality and Changes in Reproductive Hormones; A Cross-sectional Study Among 1221 Young Danish Men.” BMJ Open, 4:005462.|
|8, 10.||↲||The Office of Environmental Health Hazard Assesmnt. Retrieved from The Office of Environmental Health Hazard Assesment, Aug 1, 2019.|
|9.||↲||Merhi , Z. O., Keltz, J., & Zepantis, A. (2013). “Male Adiposity Impaires Clinical Pregnancy Rate by Invitro Fertilisation Without Affection Day 3 Embryo Quality.” Obesity, 21, 1608.|
|11, 12, 13.||↲||Kathleen, M. L., & Janice, R. L. Food and The Nutrition Care Process. St. Louis, Missouri: Elsevier, 2017.|